diff --git a/CHANGELOG.md b/CHANGELOG.md
index d440b96c..7c3fe1ba 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,6 +10,8 @@ Note: In this file, do not use the hard wrap in the middle of a sentence for com
 
 ## [Unreleased]
 
+- Update `uv@latest` to 0.11.21.
+
 - Update `protoc@latest` to 3.35.1.
 
 - Update `mise@latest` to 2026.6.9.
diff --git a/manifests/uv.json b/manifests/uv.json
index 4e52cf21..32ba5b89 100644
--- a/manifests/uv.json
+++ b/manifests/uv.json
@@ -68,10 +68,48 @@
     }
   },
   "latest": {
-    "version": "0.11.19"
+    "version": "0.11.21"
   },
   "0.11": {
-    "version": "0.11.19"
+    "version": "0.11.21"
+  },
+  "0.11.21": {
+    "x86_64_linux_musl": {
+      "etag": "0x8DEC7E61B521AAD",
+      "hash": "9dadff5b9e7b1d2d011e41852a1cbca713d9d5d88194f2eb6bd240fa4fb0a719"
+    },
+    "x86_64_macos": {
+      "etag": "0x8DEC7E61B8D9D6B",
+      "hash": "f3c8e5708a84b920c18b691214d54d2b0da6b984789caae95d47c95120cb7765"
+    },
+    "x86_64_windows": {
+      "etag": "0x8DEC7E61AD78153",
+      "hash": "ace861f360c6de2babedc1607d0f454b6b09a820dbc8182dc15af927e4df9589"
+    },
+    "aarch64_linux_musl": {
+      "etag": "0x8DEC7E6176DA407",
+      "hash": "e71badaed2a2c3a404a0a00974b51c7ed5f5bc7be947916846005b739c68a5a2"
+    },
+    "aarch64_macos": {
+      "etag": "0x8DEC7E616AAB64E",
+      "hash": "1f921d491ba5ffeea774eb04d6681ecee379101341cbb1500394993b541bf3f4"
+    },
+    "aarch64_windows": {
+      "etag": "0x8DEC7E61702D75A",
+      "hash": "74e443f8004022dde57a1bd0d10c097830f9ea8feb4ec927db52cd5d805c2f48"
+    },
+    "powerpc64le_linux_gnu": {
+      "etag": "0x8DEC7E619AC05B5",
+      "hash": "0e97021d831f9670c8261f9270ecf94b83f1a90ff5312389e37a77676deaec87"
+    },
+    "riscv64_linux_gnu": {
+      "etag": "0x8DEC7E619D751C3",
+      "hash": "63013d7afe8fd552b273a7a5ca1f1425c0c82b12d73454d24237876bc26006e9"
+    },
+    "s390x_linux_gnu": {
+      "etag": "0x8DEC7E61A441A26",
+      "hash": "743694a86a05eaf15d292c3d757388c4b2a11b4a7eb67f000077b4d6c467347e"
+    }
   },
   "0.11.20": {
     "x86_64_linux_musl": {