diff --git a/CHANGELOG.md b/CHANGELOG.md
index 56d801be..0a33b258 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,6 +10,8 @@ Note: In this file, do not use the hard wrap in the middle of a sentence for com
 
 ## [Unreleased]
 
+- Update `wasmtime@latest` to 46.0.1.
+
 - Update `wasm-bindgen@latest` to 0.2.126.
 
 - Update `vacuum@latest` to 0.29.6.
diff --git a/manifests/wasmtime.json b/manifests/wasmtime.json
index b586d9b2..3e32b284 100644
--- a/manifests/wasmtime.json
+++ b/manifests/wasmtime.json
@@ -35,13 +35,13 @@
     }
   },
   "latest": {
-    "version": "46.0.0"
+    "version": "46.0.1"
   },
   "46": {
-    "version": "46.0.0"
+    "version": "46.0.1"
   },
   "46.0": {
-    "version": "46.0.0"
+    "version": "46.0.1"
   },
   "46.0.1": {
     "x86_64_linux_gnu": {